Milan is Italy’s business hub and center of chic. It is the country’s most populous and prosperous city, serving as the capital of commerce, finance, fashion, and media. Milan is also Italy’s transport hub, with the biggest international airport, the most rail connections, and the best subway system. From St. Ambrose and Leonardo da Vinci to the waves of migrants who fueled its growth in the second half of the 20th century, outsiders have always been drawn to Milan for its open, freewheeling commercial culture and acceptance of new ideas. Virtually every invader in European history – Gaul, Roman, Goth, Longobard, and Frank – as well as a long series of rulers from France, Spain, and Austria, took a turn at ruling the city. In the Renaissance, Milan became one of the first independent city-states, but its heyday of self-rule proved comparatively brief. From 1277 until 1500, it was ruled by the Visconti and subsequently the Sforza dynasties. Today, Milan is the capital of Lombardy, the most populated and developed of Italian regions. The city proper has about 1.3 million inhabitants. Leonardo’s Last Supper and other great works of art are in Milan, as well as a spectacular Gothic Duomo, many notable churches, a synagogue, and an ancient Christian baptistery.